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Side Effects Of Coming Off Cymbalta: What You Need To Know

Stopping Cymbalta Dealing with Duloxetine Withdrawal

Are you considering discontinuing the use of Cymbalta? It’s important to be aware of the potential side effects that may occur when coming off this medication. Cymbalta, also known as duloxetine, is commonly prescribed to treat depression, anxiety, and certain types of chronic pain. While it can be an effective treatment option for many individuals, stopping the medication abruptly or without proper medical guidance can lead to withdrawal symptoms. In this article, we will discuss the possible side effects of coming off Cymbalta and provide you with some tips to help minimize any discomfort during the process.

Understanding Cymbalta Withdrawal

When you stop taking Cymbalta, your body may experience a range of withdrawal symptoms. These symptoms can vary in severity and duration, depending on factors such as the dosage you were taking, how long you were on the medication, and your individual physiology. It’s essential to note that not everyone will experience withdrawal symptoms, but it’s crucial to be prepared and informed in case you do.

Potential Side Effects

The most common side effects reported during Cymbalta withdrawal include:

1. Nausea and Vomiting: Some individuals may experience feelings of nausea and even vomiting when discontinuing Cymbalta. This can be uncomfortable but is usually temporary and should subside within a few days to a couple of weeks.

2. Dizziness and Vertigo: Cymbalta withdrawal can cause dizziness and a spinning sensation known as vertigo. These symptoms may make it challenging to maintain balance and can be accompanied by feelings of lightheadedness.

3. Brain Zaps: One of the most distinctive symptoms reported during Cymbalta withdrawal is often described as “brain zaps” or “electric shocks.” These sensations can be quite uncomfortable and feel like brief jolts or pulses in the brain.

4. Headache: Headaches are another common side effect experienced when coming off Cymbalta. These headaches can range from mild to severe and may last for several days or weeks.

5. Mood Swings: Discontinuing Cymbalta can lead to changes in mood, including irritability, anxiety, and feelings of sadness. These mood swings can be challenging to manage but are typically temporary.

6. Sleep Disturbances: Some individuals may experience difficulties sleeping or changes in sleep patterns during Cymbalta withdrawal. This can include insomnia or excessive sleepiness.

7. Flu-Like Symptoms: It’s not uncommon to experience flu-like symptoms when discontinuing Cymbalta. These symptoms can include body aches, fatigue, chills, and sweating.

8. Digestive Issues: Cymbalta withdrawal can also affect the digestive system, leading to symptoms such as diarrhea, constipation, or stomach cramps.

9. Sensory Disturbances: Some individuals may experience sensory disturbances during Cymbalta withdrawal. This can include heightened sensitivity to light, sound, or touch.

10. Electric Shock Sensations: In addition to brain zaps, some individuals may also experience electric shock sensations in other parts of the body, such as the arms or legs.

Minimizing Discomfort During Cymbalta Withdrawal

If you have decided to discontinue Cymbalta, it’s essential to do so under the guidance of a healthcare professional. They can provide you with a tapering schedule, which involves gradually reducing the dosage over time to minimize the severity of withdrawal symptoms. Here are a few additional tips to help minimize discomfort during this process:

1. Communicate with Your Doctor

Before making any changes to your medication regimen, it’s crucial to consult your doctor. They can assess your individual situation and provide you with tailored advice and a plan to safely come off Cymbalta.

2. Follow a Tapering Schedule

A tapering schedule involves gradually reducing the dosage of Cymbalta over a specified period. This helps your body adjust to the decreasing levels of the medication, reducing the severity of withdrawal symptoms.

3. Stay Hydrated

Drinking plenty of water can help alleviate some of the common side effects of Cymbalta withdrawal, such as nausea and headaches. Staying hydrated is essential for overall well-being during this transition.

4. Maintain a Healthy Lifestyle

Eating a balanced diet, getting regular exercise, and practicing stress-reducing techniques like meditation or yoga can help support your body and mind during the withdrawal process.

5. Seek Support

Don’t hesitate to reach out to a support system, whether it’s friends, family, or a therapist. Talking about your experiences and emotions can provide comfort and help you navigate the challenges of coming off Cymbalta.

6. Be Patient and Kind to Yourself

Coming off any medication can be challenging, and it’s essential to be patient with yourself throughout the process. Remember to practice self-care and prioritize your well-being as you adjust to life without Cymbalta.


While Cymbalta can be an effective treatment for various conditions, it’s crucial to be aware of the potential side effects that may occur when coming off the medication. By following a tapering schedule under the guidance of a healthcare professional and implementing self-care strategies, you can minimize discomfort and successfully transition away from Cymbalta. Remember, everyone’s experience is unique, so be patient, seek support, and prioritize your well-being throughout the process.

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